When it comes to examining the blood vessels in the eye fluorescein angiography (FA) and indocyanine green angiography (ICG) was once the only options available to doctors. Both of these imaging techniques required the use of intravenous dye injections. Common (FA) and (ICG) angiogram side effects included nausea, vomiting, headache, fainting and low blood pressure due to the invasive properties of the dyes. The limitations associated with (FA) and (ICG) angiography led doctors to perform these tests only to determine the critical diagnosis of sight-threatening complications due to diabetic retinopathy (DR), age-related macular degeneration (AMD) and other retinal vascular diseases. It was not used during routine screenings or for early diagnosis. OCTA is the latest tool used for this purpose.